国際的なImaging geneticsのコンソーシアムであるENIMAに参加して、データを提供して他施設共同研究による成果を上げています。

  1. ENIGMA-Lateralization group. Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex. Brain Imaging and Behaviour (accepted)
  2. Adams H, (203名中略) Hashimoto R,(341名中205番目)(134名中略)Thompson P. Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nature Neuroscience, (in press)
  3. Thompson P, (29名中略)Hashimoto R, (71名中31番目)Wright M, Ye J, for the ENIGMA Consortium. ENIGMA and the individual: Predicting factors that affect the brain in 35 countries worldwide. NeuroImage (in press)
  4. Hibar DP, (236名中略)Hashimoto R, (294名中238番目)(55名中略), Medland S.E. Common genetic variants influence human subcortical brain structures. Nature 9;520(7546):224-9, 2015.4
  5. Toriumi K, Kondo M, Nagai T, Hashimoto R, Ohi K, Song Z, Tanaka J, Mouri A, Koseki T, Yamamori H, Furukawa-Hibi Y, Mamiya T, Fukushima T, Takeda M, Nitta A, Yamada K, Nabeshima T. Deletion of SHATI/NAT8L increases dopamine D1 receptor on the cell surface in the nucleus accumbens, accelerating methamphetamine dependence. Int J Neuropsychopharmacol, 17:443-453, 2014.1
  6. *Hashimoto R, Hirata Y, Asada T, Yamashita F, Nemoto K, Mori T, Moriguchi Y, Kunugi H, Arima K, Ohnishi T. Effect of the BDNF and the ApoE polymorphisms on disease progression in preclinical Alzheimer's disease. Genes Brain Behav, 8(1), 43-52, 2009.2
  7. *Hashimoto R, Moriguchi Y, Yamashita F, Mori T, Nemoto K, Okada T, Hori H, Noguchi H, Kunugi H, Ohnishi T. Dose Dependent Effect of the Val66Met Polymorphism of the Brain-Derived Neurotrophic Factor Gene on Memory-Related Hippocampal Activity. Neurosci Res, 61(4):360-367, 2008.8
大阪大学大学院大阪大学・金沢大学・浜松医科大学・千葉大学・福井大学連合小児発達学研究科附属
子どものこころの分子統御機構研究センター
(大阪大学大学院医学系研究科情報統合医学講座精神医学教室 兼任)

橋本 亮太

〒565-0871 大阪府吹田市山田丘2-2,D3
TEL:06-6879-3074 FAX:06-6879-3074
E-mail:hashimor@psy.med.osaka-u.ac.jp